Nature Reviews Rheumatology
2024
Engineering approaches for RNA-based and cell-based osteoarthritis therapies
Carlisle R. DeJulius, Bonnie L. Walton, Juan M. Colazo, Richard d’Arcy, Nora Francini, Jonathan M. Brunger & Craig L. Duvall
Nature Communications
2024
Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy
Ella N. Hoogenboezem, Shrusti S. Patel, Justin H. Lo, Ashley B. Cavnar, Lauren M. Babb, Nora Francini, Eva F. Gbur, Prarthana Patil, Juan M. Colazo, Danielle L. Michell, Violeta M. Sanchez, Joshua T. McCune, Jinqi Ma, Carlisle R. DeJulius, Linus H. Lee, Jonah C. Rosch, Ryan M. Allen, Larry D. Stokes, Jordan L. Hill, Kasey C. Vickers, Rebecca S. Cook & Craig L. Duvall
Antioxidants
2023
Intraocular Sustained Release of EPO-R76E Mitigates Glaucoma Pathogenesis by Activating the NRF2/ARE Pathway
Sarah Naguib, Carlisle R. DeJulius, Jon R. Backstrom, Ameer A. Haider, John M. Ang, Andrew M. Boal, David J. Calkins, Craig L. Duvall and Tonia S. Rex
Biomaterials
2023
Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing
Shrusti S. Patel, Ella N. Hoogenboezem, Fang Yu, Carlisle R. DeJulius, Brock Fletcher, Alex G. Sorets, Fiona K. Cherry, Justin H. Lo, Mariah G. Bezold, Nora Francini, Richard d’Arcy, Jordan E. Brasuell, Rebecca S. Cook, Craig L. Duvall
Nature Biomedical Engineering
2023
Suppression of local inflammation via galectin-anchored indoleamine 2,3-dioxygenase
Evelyn Bracho-Sanchez, Fernanda G. Rocha, Sean K. Bedingfield, Brittany D. Partain, Sabrina L. Macias, Maigan A. Brusko, Juan M. Colazo, Margaret M. Fettis, Shaheen A. Farhadi, Eric Y. Helm, Kevin Koenders, Alexander J. Kwiatkowski, Antonietta Restuccia, Bethsymarie Soto Morales, Arun Wanchoo, Dorina Avram, Kyle D. Allen, Craig L. Duvall, Shannon M. Wallet, Gregory A. Hudalla & Benjamin G. Keselowsky
Advanced Functional Materials
2023
Hybrid Shear-Thinning Hydrogel Integrating Hyaluronic Acid with ROS-Responsive Nanoparticles
Mariah G. Bezold, Andrew R. Hanna, Bryan R. Dollinger, Prarthana Patil, Fang Yu, Craig L. Duvall, Mukesh K. Gupta
Cells
2023
Newly Developed Di-Block Copolymer-Based Cell Membrane Stabilizers Protect Mouse Coronary Artery Endothelial Cells against Hypoxia/Reoxygenation Injury
Zhu Li, Mukesh K. Gupta, Matthew B. Barajas, Takuro Oyama, Craig L. Duvall, and Matthias L. Riess
ACS Nano
2023
Nonviral In Vivo Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles
R. Brock Fletcher, Larry D. Stokes, Isom B. Kelly III, Katelyn M. Henderson, Isabel C. Vallecillo-Viejo, Juan M. Colazo, Benjamin V. Wong, Fang Yu, Richard d’Arcy, Morgan N. Struthers, Brian C. Evans, Jacob Ayers, Matthew Castanon, Michael J. Weirich, Sarah K. Reilly, Shrusti S. Patel, Yoanna I. Ivanova, Carlos A. Silvera Batista, Sharon M. Weiss, Charles A. Gersbach, Jonathan M. Brunger, and Craig L. Duvall
Nature Cell Biology
2022
Microbial small RNAs on LDL promote atherosclerosis-associated inflammation through macrophage TLR8
RM Allen, DL Michell, AB Cavnar, W Zhu, N Makhijani, DL Contreras, CA Raby, EM Semler, C DeJulius, M Castleberry, Y Zhang, M Ramirez-Solano, S Zhao, CL Duvall, AC Doran, Q Sheng, MF Linton, KC Vickers
Journal of the American Chemical Society
2022
A Reactive Oxygen Species-Scavenging ‘Stealth’ Polymer, Poly(thioglycidyl glycerol), Outperforms Poly(ethylene glycol) in Protein Conjugates and Nanocarriers and Enhances Protein Stability to Environmental and Biological Stressors
R d’Arcy, F El Mohtadi, N Francini, CR DeJulius, H Back, A Gennari, M Geven, M Lopez-Cavestany, ZY Turhan, F Yu, JB Lee, MR King, L Kagan, CL Duvall, N Tirelli
Molecular Reproduction and Development
2022
Nanoparticle-mediated transgene expression of insulin-like growth factor 1 in the growth restricted guinea pig placenta increases placenta nutrient transporter expression and fetal glucose concentrations
RL Wilson, K Lampe, MK Gupta, CL Duvall, HN Jones
ACS Chemical Biology
2022
Discovery of a Redox-Activatable Chemical Probe for Detection of Cyclooxygenase-2 in Cells and Animals
MJ Uddin, JH Lo, CG Oltman, BC Crews, T Huda, J Liu, PJ Kingsley, S Lin, M Milad, AM Aleem, A Asaduzzaman, JO McIntyre, CL Duvall, LJ Marnett
Science Translational Medicine
2022
ROS-Degradable Polythioketal Urethane Foam Dressings to Promote Porcine Skin Wound Repair
P Patil, KA Russo, JT McCune, AC Pollins, MA Cottam, BR Dollinger, CR DeJulius, MK Gupta, R D’Arcy, JM Colazo, F Yu, MG Bezold, JR Martin, NL Cardwell, JM Davidson, CM Thompson, A Barbul, AM Hasty, SA Guelcher, CL Duvall
Biophysical Journal
2022
Visualizing the lipid dynamics role in infrared neural stimulation using stimulated Raman scattering
WR Adams, R Gautam, A Locke, Masson LE, AI Borrachero-Conejo, B Dollinger†, GA Throckmorton, CL Duvall, ED Jansen, A Mahadevan-Jansen
Cellular and Molecular Bioengineering
2022
Albumin-Binding Aptamer Chimeras for Improved siRNA Bioavailability
JC Rosch, EN Hoogenboezem, AG Sorets, CL Duvall*, ES Lippmann*
JCI Insight
2021
Therapeutic MK2 Inhibition Blocks Pathological Vascular Smooth Muscle Cell Phenotype Switch
JW Tierney, BC Evans, J Cheung-Flynn, B Wang, JM Colazo, ME Polcz, RS Cook, CM Brophy, CL Duvall.
Nature Biomedical Engineering
2021
Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage
SK Bedingfield, JM Colazo, F Yu, DD Liu, MA Jackson, LE Himmel, H Cho, LJ Crofford, KA Hasty, CL Duvall
ACS Nano
2021
Top-Down Fabricated microPlates for Prolonged, Intra-articular Matrix Metalloproteinase 13 siRNA Nanocarrier Delivery to Reduce Post-traumatic Osteoarthritis
SK Bedingfield, JM Colazo, M Di Francesco, F Yu, DD Liu, V Di Francesco, LE Himmel, MK Gupta, H Cho, KA Hasty, P Decuzzi, CL Duvall
ACS Applied Materials and Interfaces
2021
Shape-Defined microPlates for the Sustained Intra-articular Release of Dexamethasone in the Management of Overload-Induced Osteoarthritis
M Di Francesco, SK Bedingfield, V Di Francesco, JM Colazo, F Yu, L Ceseracciu, E Bellotti, D Di Mascolo, M Ferreira, LE Himmel, CL Duvall*, P Decuzzi*
Materials
2021
Settable Polymeric Autograft Extenders in a Rabbit Radius Model of Bone Formation
LA Boller, MA McGough, SM Shiels, CL Duvall, JC Wenke, SA Guelcher
Acta Biomaterials
2021
Effects of nanocrystalline hydroxyapatite concentration and skeletal site on bone and cartilage formation in rats
LA Boller, SM Shiels, DC Florian, SH Peck, JG Schoenecker, CL Duvall, JC Wenke, SA Guelcher
Bioconjugate Chemistry
2021
Optimizing an Antioxidant TEMPO Copolymer for Reactive Oxygen Species Scavenging and Anti-Inflammatory Effects in Vivo
CR DeJulius, BR Dollinger, TE Kavanaugh, E Dailing, F Yu, S Gulati, A Miskalis, C Zhang, J Uddin, S Dikalov, CL Duvall
Acta Biomaterials
2021
Hydrogel microspheres for spatiotemporally controlled delivery of RNA and silencing gene expression within scaffold-free tissue engineered constructs
A McMillan, MK Nguyen, CT Huynh, SM Sarett, G Peilin, M Chetverikova, K Nguyen, D Grosh, CL Duvall, E Alsberg
Journal of Controlled Release
2021
Microsphere antioxidant and sustained erythropoietin-R76E release functions cooperate to reduce traumatic optic neuropathy
CR DeJulius, A Bernardo-Colón, S.Naguib, JR Backstrom, T.Kavanaugh, MK.Gupta, CL Duvall*, TS Rex
Advanced Therapeutics
2021
Recent Advances in Clinical Translation of Intra‐Articular Osteoarthritis Drug Delivery Systems
CR DeJulius, S Gulati, KA Hasty, LJ Crofford, CL Duvall
