Publications

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ACS Applied Materials and Interfaces
2020

Modifying cell membranes with anionic polymer amphiphiles potentiates intracellular delivery of cationic peptides

EA Dailing, KV Kilchrist, JW Tierney, RB Fletcher, BC Evans, CL Duvall
ACS Central Science
2020

Structural Optimization of Polymeric Carriers to Enhance the Immunostimulatory Activity of Molecularly Defined RIG-I Agonists

ME Jacobson, KW Becker, CR Palmer, LE Pastora, RB Fletcher, KA Collins, O Fedorova, CL Duvall, AM Pyle, JT Wilson
ACS Chemical Biology
2020

Visualizing HIF-1α mRNA in a Subpopulation of Bone Marrow-Derived Cells to Predict Retinal Neovascularization

MI Uddin, TC Kilburn, CL Duvall, JS Penn
ACS Applied Materials and Interfaces
2020

Tuning Composition of Polymer and Porous Silicon Composite Nanoparticles for Early Endosome Escape of Anti-microRNA Peptide Nucleic Acids

IB Kelly, RB Fletcher, JR McBride, SM Weiss, CL Duvall
ACS Sensors
2020

Genetically Encoded Split-Luciferase Biosensors to Measure Endosome Disruption Rapidly in Live Cells

KV Kilchrist, JW Tierney, CL Duvall
Pharmaceutical Research
2020

DNA Polyplexes of a Phosphorylcholine-Based Zwitterionic Polymer for Gene Delivery

KM Dave, L Han, MA Jackson, L Kadlecik, CL Duvall, DS Manickam
ACS Medicinal Chemistry Letters
2020

Molecular Imaging of Inflammation in Osteoarthritis Using a Water-soluble Fluorocoxib

MJ Uddin, A Vemulapalli, H Niitsu, BC Crews, CG Oltman, PJ Kingsley, TE Kavanaugh, SK Bedingfield, JO McIntyre, M Milad, AM Aleem, RJ Coffey, CL Duvall, LJ Marnett
ACS Nano
2020

Tuning Ligand Density to Optimize Pharmacokinetics of Targeted Nanoparticles for Dual Protection against Tumor-Induced Bone Destruction

JP Vanderburgh, JL Hill, MK Gupta, KA Kwakwa, SK Wang, KE Moyer, SK Bedingfield, AR Merkel, R d’Arcy SA Guelcher, JA Rhoades, CL Duvall
ACS Applied Materials and Interfaces
2020

Endosomolytic mesoporous silica nanoparticles for siRNA/miRNA combination therapy of metastatic cancer

Y Wang, Y Xie, J Li, KV Kilchrist, CL Duvall, D Oupický
ACS Biomaterials Science & Engineering
2020

Nanocrystalline hydroxyapatite-poly(thioketal urethane) nanocomposites stimulate a combined intramembranous and endochondral ossification response in rabbits

M McGough, L Boller, D Groff, J Schoenecker, J Nyman, JC Wenke, C Rhodes, D Shimko, CL Duvall, SA Guelcher
Nature Communications
2019

Optimization of an Anionic, Endosome-Escaping Polymer to Potentiate Intracellular Delivery of Cationic Peptides, Biomacromolecules, and Nanoparticles

BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, M Oliver, J Cheung-Flynn, CM Brophy, JW Tierney, JS Isenberg, KD Hankenson, K Ghimire, C Lander, CA Gersbach, CL Duvall
Journal of Controlled Release
2019

Systemic Delivery of a Gli Inhibitor via Polymeric Nanocarriers Blocks Tumor-Induced Bone Disease

JP Vanderburgh, KA Kwakwa, TA Werfel, AR Merkel, MK Gupta, RW Johnson, SA Guelcher, CL Duvall, JA Rhoades Sterling
ACS Omega
2019

Optimizing Conjugation Efficiency and Residual Copper-Associated Toxicity in CuAAC-Functionalized Polyplexes for Delivery to Tumor-Associated Macrophages

EB Glass, S Masjedi, SO Dudzinski, AJ Wilson, CL Duvall, FE Yull, TD Giorgio
Tissue Engineering B
2019

Applied Bioengineering in Tissue Reconstruction, Replacement, and Regeneration

JM Colazo, BC Evans, AF Farinas, S Al-Kassis, CL Duvall. WP Thayer
European Journal of Pharmaceutical Science
2019

Preparation, preliminary pharmacokinetic and brain targeting study of metformin encapsulated W/O/W composite submicron emulsions promoted by borneol

L Hong, X Li, Y Bao, CL Duvall, C Zhang, W Chen, C Peng
Cellular and Molecular Bioengineering
2019

PLGA Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles

K Garland, S Sevimli, KV Kilchrist, CL Duvall, RS Cook, JT Wilson
AJP-Endocrinology and Metabolism
2019

Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis

N Mignemi, P McClatchey, KV Kilchrist, I Williams, B Millis, K Syring, CL Duvall, D Wasserman, O McGuinness
ACS Nano
2019

Gal8 Visualization of Endosome Disruption Predicts Carrier-mediated Biologic Drug Intracellular Bioavailability

KV Kilchrist, SC Dimobi, MA Jackson, BC Evans, TA Werfel, EA Dailing, SK Bedingfield, IB Kelly, CL Duvall
Biomaterials
2019

Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes

MA Jackson, SK Bedingfield, F Yu, ME Stokan, RE Miles, EJ Curvino, EN Hoogenboezem, RH Bonami, SS Patel, PL Kendall, TD Giorgio, CL Duvall
Tissue Engineering A
2019

Poly(thioketal urethane) Autograft Extenders in an Intertransverse Process Model of Bone Formation

MAP McGough, SM Shiels, LA Boller, KJ Zienkiewicz, CL Duvall, JC Wenke, SA Guelcher
Tissue Engineering A
2019

Nanotechnology enabled modulation of signaling pathways affects physiologic responses in intact vascular tissue

KM Hocking, BC Evans, P Komalavilas, J Cheung-Flynn CL Duvall, and CM Brophy
Advanced Drug Delivery Reviews
2018

Harnessing Albumin as a Carrier for Cancer Therapies

EN Hoogenboezem, CL Duvall
Journal of Controlled Release
2018

Excipients for the Lyoprotection of MAPKAP Kinase 2 Inhibitory Peptide Nano-Polyplexes

AJ Mukalel, BC Evans, KV Kilchrist, EA Dailing, B Burdette, J Cheung-Flynn, CM Brophy, CL Duvall
Cancer Research
2018

Selective mTORC2 inhibitor therapeutically blocks breast cancer cell growth and survival

TA Werfel, S Wang, MA Jackson, TE Kavanaugh, MM Joly, L Lee, DJ Hicks, VM Sanchez, PI Gonzalez-Ericsson, KV Kilchrist, SC Dimobi, SM Sarett, DM Brantley-Sieders , RS Cook, CL Duvall
Journal of Biomedical Materials Research A
2018

Formulation and characterization of poly(propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles for pH-dependent membrane disruption and cytosolic delivery

LP Fernando, JS Lewis, BC Evans, CL Duvall, BG Keselowsky