Biomaterials
2020
Kupffer Cell Release of Platelet Activating Factor Drives Dose Limiting Toxicities of Nucleic Acid Nanocarriers
Jackson MA, Patel SS, Yu Fang, Cottam MA, Glass EB, Hoogenboezem EN, Fletcher RB, Dollinger BR, Patil P, Liu Danielle, Kelly IB, Bedingfield SK, King AR, Miles RE, Hasty AM, Giorgio TD, Duvall CL
Advanced Healthcare Materials
2020
Amphiphilic Polyelectrolyte Graft Copolymers Enhance the Activity of Cyclic Dinucleotide STING Agonists
Nguyen DC, Shae D, Pagendarm HM, Becker KW, Wehbe M, Kilchrist KV, Pastora LE, Palmer CR, Seber P, Christov PP, Duvall CL, Wilson JT
Current Opinion in Chemical Engineering
2020
Caveolae-mediated transport at the injured blood–brain barrier as an underexplored pathway for central nervous system drug delivery
AG Sorets, JC Rosch, CL Duvall, ES Lippmann
Biomaterials
2020
Enhanced stem cell retention and antioxidative protection with injectable, ROS-degradable PEG hydrogels
JR Martin, P Patil, F Yu, MK Gupta, CL Duvall
ACS Applied Materials and Interfaces
2020
Modifying cell membranes with anionic polymer amphiphiles potentiates intracellular delivery of cationic peptides
EA Dailing, KV Kilchrist, JW Tierney, RB Fletcher, BC Evans, CL Duvall
ACS Central Science
2020
Structural Optimization of Polymeric Carriers to Enhance the Immunostimulatory Activity of Molecularly Defined RIG-I Agonists
ME Jacobson, KW Becker, CR Palmer, LE Pastora, RB Fletcher, KA Collins, O Fedorova, CL Duvall, AM Pyle, JT Wilson
ACS Chemical Biology
2020
Visualizing HIF-1α mRNA in a Subpopulation of Bone Marrow-Derived Cells to Predict Retinal Neovascularization
MI Uddin, TC Kilburn, CL Duvall, JS Penn
ACS Applied Materials and Interfaces
2020
Tuning Composition of Polymer and Porous Silicon Composite Nanoparticles for Early Endosome Escape of Anti-microRNA Peptide Nucleic Acids
IB Kelly, RB Fletcher, JR McBride, SM Weiss, CL Duvall
ACS Sensors
2020
Genetically Encoded Split-Luciferase Biosensors to Measure Endosome Disruption Rapidly in Live Cells
KV Kilchrist, JW Tierney, CL Duvall
Pharmaceutical Research
2020
DNA Polyplexes of a Phosphorylcholine-Based Zwitterionic Polymer for Gene Delivery
KM Dave, L Han, MA Jackson, L Kadlecik, CL Duvall, DS Manickam
ACS Medicinal Chemistry Letters
2020
Molecular Imaging of Inflammation in Osteoarthritis Using a Water-soluble Fluorocoxib
MJ Uddin, A Vemulapalli, H Niitsu, BC Crews, CG Oltman, PJ Kingsley, TE Kavanaugh, SK Bedingfield, JO McIntyre, M Milad, AM Aleem, RJ Coffey, CL Duvall, LJ Marnett
ACS Nano
2020
Tuning Ligand Density to Optimize Pharmacokinetics of Targeted Nanoparticles for Dual Protection against Tumor-Induced Bone Destruction
JP Vanderburgh, JL Hill, MK Gupta, KA Kwakwa, SK Wang, KE Moyer, SK Bedingfield, AR Merkel, R d’Arcy SA Guelcher, JA Rhoades, CL Duvall
ACS Applied Materials and Interfaces
2020
Endosomolytic mesoporous silica nanoparticles for siRNA/miRNA combination therapy of metastatic cancer
Y Wang, Y Xie, J Li, KV Kilchrist, CL Duvall, D Oupický
ACS Biomaterials Science & Engineering
2020
Nanocrystalline hydroxyapatite-poly(thioketal urethane) nanocomposites stimulate a combined intramembranous and endochondral ossification response in rabbits
M McGough, L Boller, D Groff, J Schoenecker, J Nyman, JC Wenke, C Rhodes, D Shimko, CL Duvall, SA Guelcher
Nature Communications
2019
Optimization of an Anionic, Endosome-Escaping Polymer to Potentiate Intracellular Delivery of Cationic Peptides, Biomacromolecules, and Nanoparticles
BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, M Oliver, J Cheung-Flynn, CM Brophy, JW Tierney, JS Isenberg, KD Hankenson, K Ghimire, C Lander, CA Gersbach, CL Duvall
Journal of Controlled Release
2019
Systemic Delivery of a Gli Inhibitor via Polymeric Nanocarriers Blocks Tumor-Induced Bone Disease
JP Vanderburgh, KA Kwakwa, TA Werfel, AR Merkel, MK Gupta, RW Johnson, SA Guelcher, CL Duvall, JA Rhoades Sterling
ACS Omega
2019
Optimizing Conjugation Efficiency and Residual Copper-Associated Toxicity in CuAAC-Functionalized Polyplexes for Delivery to Tumor-Associated Macrophages
EB Glass, S Masjedi, SO Dudzinski, AJ Wilson, CL Duvall, FE Yull, TD Giorgio
Tissue Engineering B
2019
Applied Bioengineering in Tissue Reconstruction, Replacement, and Regeneration
JM Colazo, BC Evans, AF Farinas, S Al-Kassis, CL Duvall. WP Thayer
European Journal of Pharmaceutical Science
2019
Preparation, preliminary pharmacokinetic and brain targeting study of metformin encapsulated W/O/W composite submicron emulsions promoted by borneol
L Hong, X Li, Y Bao, CL Duvall, C Zhang, W Chen, C Peng
Cellular and Molecular Bioengineering
2019
PLGA Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles
K Garland, S Sevimli, KV Kilchrist, CL Duvall, RS Cook, JT Wilson
AJP-Endocrinology and Metabolism
2019
Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis
N Mignemi, P McClatchey, KV Kilchrist, I Williams, B Millis, K Syring, CL Duvall, D Wasserman, O McGuinness
ACS Nano
2019
Gal8 Visualization of Endosome Disruption Predicts Carrier-mediated Biologic Drug Intracellular Bioavailability
KV Kilchrist, SC Dimobi, MA Jackson, BC Evans, TA Werfel, EA Dailing, SK Bedingfield, IB Kelly, CL Duvall
Biomaterials
2019
Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes
MA Jackson, SK Bedingfield, F Yu, ME Stokan, RE Miles, EJ Curvino, EN Hoogenboezem, RH Bonami, SS Patel, PL Kendall, TD Giorgio, CL Duvall
Tissue Engineering A
2019
Poly(thioketal urethane) Autograft Extenders in an Intertransverse Process Model of Bone Formation
MAP McGough, SM Shiels, LA Boller, KJ Zienkiewicz, CL Duvall, JC Wenke, SA Guelcher
Tissue Engineering A
2019
Nanotechnology enabled modulation of signaling pathways affects physiologic responses in intact vascular tissue
KM Hocking, BC Evans, P Komalavilas, J Cheung-Flynn CL Duvall, and CM Brophy
