Publications

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Biomaterials
2019

Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes

MA Jackson, SK Bedingfield, F Yu, ME Stokan, RE Miles, EJ Curvino, EN Hoogenboezem, RH Bonami, SS Patel, PL Kendall, TD Giorgio, CL Duvall
Tissue Engineering A
2019

Poly(thioketal urethane) Autograft Extenders in an Intertransverse Process Model of Bone Formation

MAP McGough, SM Shiels, LA Boller, KJ Zienkiewicz, CL Duvall, JC Wenke, SA Guelcher
Tissue Engineering A
2019

Nanotechnology enabled modulation of signaling pathways affects physiologic responses in intact vascular tissue

KM Hocking, BC Evans, P Komalavilas, J Cheung-Flynn CL Duvall, and CM Brophy
Advanced Drug Delivery Reviews
2018

Harnessing Albumin as a Carrier for Cancer Therapies

EN Hoogenboezem, CL Duvall
Journal of Controlled Release
2018

Excipients for the Lyoprotection of MAPKAP Kinase 2 Inhibitory Peptide Nano-Polyplexes

AJ Mukalel, BC Evans, KV Kilchrist, EA Dailing, B Burdette, J Cheung-Flynn, CM Brophy, CL Duvall
Cancer Research
2018

Selective mTORC2 inhibitor therapeutically blocks breast cancer cell growth and survival

TA Werfel, S Wang, MA Jackson, TE Kavanaugh, MM Joly, L Lee, DJ Hicks, VM Sanchez, PI Gonzalez-Ericsson, KV Kilchrist, SC Dimobi, SM Sarett, DM Brantley-Sieders , RS Cook, CL Duvall
Journal of Biomedical Materials Research A
2018

Formulation and characterization of poly(propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles for pH-dependent membrane disruption and cytosolic delivery

LP Fernando, JS Lewis, BC Evans, CL Duvall, BG Keselowsky
Cell Death and Disease
2018

Intrinsic Apoptotic Pathway Activation Increases Response to Anti-Estrogens in Luminal Breast Cancers

MM Williams, L Lee, TA Werfel, MM Joly, DJ Hicks, B Rahman, D Elion, C McKernan, V Sanchez, V Estrada, S Massarweh, R Elledge, CL Duvall, RS Cook
ACS Biomaterials Science & Engineering
2018

Drug Free ROS Sponge Polymeric Microspheres Reduce Tissue Damage from Ischemic and Mechanical Injury

KP O’Grady, TE Kavanaugh, H Cho, H Ye, MK Gupta, MC Madonna, J Lee, CM O’Brien, MC Skala, KA Hasty, CL Duvall
Advanced Functional Materials
2017

Thermogelling, ABC Triblock Copolymer Platform for Resorbable Hydrogels with Tunable, Degradation-Mediated Drug Release

MK Gupta, JR Martin, BR Dollinger, ME Hattaway, CL Duvall
Tissue Engineering Part C: Methods
2017

Porcine Ischemic Wound Healing Model for Preclinical Testing of Degradable Biomaterials

P Patil, JR Martin, SM Sarett, AC Pollins, NL Cardwell, JM Davidson, SA Guelcher, LB Nanney, CL Duvall
Tissue Engineering A
2017

ROS-shielding hydrogel for the delivery of adherent and non-adherent therapeutic cell types

BR Dollinger, MK Gupta, JR Martin, CL Duvall
PNAS
2017

Lipophilic siRNA Targets Albumin in Situ and Promotes Bioavailability, Tumor Penetration, and Carrier-Free Gene Silencing

SM Sarett, TA Werfel, L Lee, MA Jackson, KV Kilchrist, DM Brantley-Sieders, CL Duvall
Bioengineering & Translational Medicine
2017

Poly(2-propylacrylic acid) / poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation

L Yang, E Bracho-Sanchez, MR Carstens, LP Fernando, JS Lewis, CL Duvall, BG Keselowsky
ACS Nano
2017

Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol

MA Jackson, TA Werfel, E Curvino, F Yu, TE Kavanaugh, SM Sarett, M Dockery, KV Kilchrist, A Jackson, TD Giorgio, CL Duvall
Journal of Controlled Release
2017

Combinatorial Optimization of PEG Architecture and Hydrophobic Content Improves siRNA Polyplex Stability, Pharmacokinetics, and Potency In Vivo

TA Werfel, MA Jackson, TE Kavanaugh, KC Kirkbride, M Miteva, TD Giorgio, CL Duvall
Perfusion
2017

Unregulated saphenous vein graft distension decreases tissue viscoelasticity

ES Wise, KM Hocking, BC Evans, CL Duvall, J Cheung-Flynn, CM Brophy
Advanced Healthcare Materials
2016

Local delivery of PHD2 siRNA from ROS-degradable scaffolds to promote diabetic wound healing

JR Martin, CE Nelson, MK Gupta, F Yu, SM Sarett, KM Hocking, AC Pollins, LB Nanney, JM Davidson, SA Guelcher, CL Duvall
RSC Advances
2016

Oxidatively Degradable Poly(thioketal urethane)/Ceramic Composite Bone Cements with Bone-Like Strength

MA McEnery, S Lu, MK Gupta, KJ Zienkiewicz, JC Wenke, KN Kalpakci, D Shimko, CL Duvall, SA Guelcher
Frontiers in Bioengineering and Biotechnology
2016

Subfailure overstretch injury leads to reversible functional impairment and purinergic P2X7 receptor activation in intact vascular tissue

W Luo, CM Guth, O Jolayemi, CL Duvall, CM Brophy, J Cheung-Flynn
Advanced Materials
2016

Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as anti-microRNA Therapies

KR Beavers, TA Werfel, T Shen, TE Kavanaugh, KV Kilchrist, JW Mares, JS Fain, CB Wiese, KC Vickers, SM Weiss, CL Duvall
Journal of Visualized Experiments
2016

Sustained Administration of β-cell Mitogens to Intact Mouse Islets Ex Vivo using Biodegradable Poly(Lactic-Co-Glycolic Acid) Microspheres

RC Pasek, TE Kavanaugh, CL Duvall, MA Gannon
Cellular and Molecular Bioengineering
2016

Mechanism of Enhanced Cellular Uptake and Cytosolic Retention of MK2 Inhibitory Peptide Nano-polyplexes

KV Kilchrist, BC Evans, CM Brophy, CL Duvall
Biomaterials
2016

Hydrophobic Interactions between Polymeric Carrier and Palmitic Acid-Conjugated siRNA Improve PEGylated Polyplex Stability and Enhance In Vivo Pharmacokinetics and Tumor Gene Silencing

SM Sarett, TA Werfel, I Chandra, MA Jackson, TE Kavanaugh, ME Hattaway, TD Giorgio, CL Duvall
Biomaterials
2016

Fluorocoxib A Loaded Nanoparticles Enable Targeted Visualization of Cyclooxygenase-2 in Inflammation and Cancer

MJ Uddin, TA Werfel, BC Crews, MK Gupta, TE Kavanaugh, PJ Kingsley, K Boyd, LJ Marnett, CL Duvall